Newsletter
From Telecom to THC: How an Engineer Tackled Alzheimer's Agitation
An engineer's path from NASDAQ IPO to hemp-derived THC trials reveals the operational realities many clin ops teams don't discuss.
Brandon Li
Newsletter
The Clinical Execution Playbook Behind Schizophrenia's First New Mechanism
How Karuna's former CMO turned disciplined trial methodology into a $14 billion BMS acquisition
Newsletter
Your Sites Are Losing Patients on Phone Screens (And You'd Never Know)
Why the gap between 'interested patient' and 'scheduled screening' is costing you enrollment
Newsletter
The Alzheimer's Hypothesis Big Pharma Missed
Why a former Genentech director bet on cortisol over amyloid, and what pilot data showing 5x better efficacy could mean for patients
Newsletter
Human or AI Voice Agents? Choosing the Right Pre-Screening Model for Your Trial
What happens when a qualified patient is ready to engage... and nobody's available to respond?
Newsletter
6 Ways to Actually Use AI in Clin Ops (w/o the Hype)
Why smart clin ops teams focus on practical AI wins instead of chasing shiny objects
Newsletter
Clin Ops Masterclass: Michael Gold on Executing Excellence at Scale
See below for our top-5 takeaways from the recent podcast
Newsletter
The 6-Month Recruitment Misconception: Why Late Starts Impact Trial Success
Why waiting until "6 months left" dramatically increases your risk of missing enrollment deadlines
Newsletter
The Alzheimer's Target Everyone Missed
Dan's team is going after what they believe are "the real toxic drivers"
Newsletter
The ROI Reality Check: Three Financial Levers To Quantify Your Patient Recruitment Investments
Why clin ops’ leaders who understand these metrics never question recruitment budgets again
Newsletter
Why Every Trial Needs a Heat Map (& How to Do It!)
Why we started monitoring sites like coaches track their star players
Newsletter
The 60-Day Pipeline: From Funnel to Flow
Why the best sites think in weekly cohorts, not conversion rates